This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Immunogen information
Immunogen - A synthesized peptide derived from human Prohibitin.
Sequence -
Gene ID - 5245
Swiss prot - P35232
Synonyms - HEL-215; HEL-S-54e; PHB1; PHB; Prohibitin
Calculated MW - 30kDa
Observed MW - 30KDa
Applications
Reactivity - Human, Mouse, Rat
Tested applications - WBIHC
Recommended dilution - WB 1:500 - 1:2000
IHC 1:50 - 1:200
Storage buffer - Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Application key - Western blotting Immunohistochemistry
Positive samples - U-87MG, A-549, MCF7, Mouse brain, Mouse heart, Mouse kidney, Rat heart, Rat liver, Rat kidney
Cellular location