Rubella test kit 091003
for researchIgGvirus

rubella test kit
rubella test kit
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Characteristics

Applications
rubella, for research
Tested parameter
IgG
Micro-organism
virus
Sample type
plasma
Analysis mode
ELISA

Description

Enzyme ImmunoAssay (ELISA) for the determination of IgM antibodies to Rubella Virus in human plasma and sera with the "capture" system. The device is intended for the follow-up of Rubella Virus infected patients and for the monitoring of risk of neonatal defects due to Rubella Virus infection during pregnancy. For Research Use Only. Introduction Rubella is a small spherical enveloped virus, 55-60nm in diameter, and is the only member of the genus Rubivirus of the family Togaviridiae. The virus contains a single positive stranded 42s RNA molecule and only one serotype is known. The virus encodes for at least three envelope glycoproteins, E1, E2a, E2b; a nucleocapsid-associated protein, C; and two nonstructural proteins. The detection of Rubella-specific IgG and IgM antibodies is very important for the serological diagnosis of both congenital and primary postnatal rubella infections as they can lead to severe birth defects. The absence of Rubella-specific IgG antibodies in sera, characteristically of long-term duration after primary infections, in presence of virus-specific IgM, is indicative for the risk of defects in newborn infants. Highly specific Rubella IgM assays, based on the IgM-capture system, are now able to provide the clinician with a helpful and reliable test for the monitoring of these risks in pregnancy.

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