Syphilis test kit EIAgen

IgGIgMlithium

The EIAgen Syphilis Ab Kit assay, is a third generation solid phase enzyme immunoassay for the qualitative detection of antibodies to Treponema pallidum (TP) in human sera or plasma (EDTA, Heparin Lithium, Sodium Citrate). This kit is for in vitro diagnostic use by a health-care professional and will not be sold to the general public. For “in vitro” diagnostic use only. Introduction Syphilis is a disease caused by infection with the spirochete bacterium Treponema pallidum, ordinarily transmitted by sexual contact. However, it can also be transmitted congenitally by transplacental passage of T. pallidum to the foetus and by blood transfusion. The serological diagnosis of syphilis is performed demonstrating the presence of significant levels of specific T. pallidum antibodies in the patient serum or plasma sample. The reference method used is the FTA-ABS technique that allows the detection of both IgG and IgM. However, its execution is laborious and the interpretation of results not simple. Alternative methods have therefore been introduced to simplify the procedure: reaction with lipoidal antigens (the reagin test) or agglutination of erythrocytes coated with specific T. pallidum antigens (hemmagglutination test or TPHA). The TPHA is the preferred technique for screening purposes, since that it detects specific IgG and IgM. Unfortunately, the result of the test is determined by subjective interpretation and cannot be completely automated. EIAgen Syphilis Ab Kit allows screening of specific IgG and IgM antibodies with the ELISA technique.