MOLgen MTBC/NTM Real Time PCR Kit is designed for the qualitative simultaneous detection of DNA of MTB Complex (MTBC) and non-tuberculous mycobacteria (NTM) of clinical interest (Mycobacterium abscessus, Mycobacterium massiliense, Mycobacterium parascrofulaceum, Mycobacterium kansasii, Mycobacterium tuberculosis, Mycobacterium avium complex, Mycobacterium intracellulare, Mycobacterium gordonae, Mycobacterium senegalense, Mycobacterium smegmatis, Mycobacterium szulgai, Mycobacterium marinum, Mycobacterium malmoense, Mycobacterium xenopi, Mycobacterium fortuitum) by Real Time Polymerase Chain Reaction (PCR) from DNA extracted from decontaminated human respiratory specimens such as sputum and bronchoalveolar lavage fluid (BALF).
Introduction
Tubercolosis (TB) is caused by Mycobacterium tuberculosis complex (MTBC) and it mainly affects the lungs. Mycobacterium tuberculosis complex (MTBC) may cause Tubercolosis in human and other animal range hosts: human hosts (infection caused by M. tuberculosis, M. africanum, M. canettii), bovine hosts (infection caused by M. bovis), caprine hosts (infection caused by M. caprae), rodent hosts (infection caused by M. microti), seal hosts (infection caused by M. pinnipedi).
TB is spread through droplets and aerosol in the air when people with lung TB cough, sneeze or spit. A person needs to inhale only a few germs to become infected. Every year, 10 million people fall ill with tuberculosis (TB). Despite being a preventable and curable disease, 1.5 million people die from TB each year – making it the main cause of pathogen agent death in the world.