Polymorphism in factor V gene R2 can be a potential risk factor for the development of venous thromboembolism (VTE). The factor V R2 polymorphism is associated with decreased levels of factor V and it drastically increases the risk of venous thrombosis in individuals who are heterozygous for the factor V Leiden mutation. Combination of the R2 Polymorphism with factor V Leiden increases the risk of venous thrombosis by 16 times.
Product details:
The assay is an in vitro PCR reaction assay for the Qualitative determination of R2 Polymorphism of factor V Leiden in the human sample such as Whole Blood and based on Taqman detection method for R2 Polymorphism Factor V (Leiden mutation) with high sensitive one step qPCR kit.
The Zena Max Factor V R2 Polymorphism PCR kit is very sensitive under our validation methods and devices. The specificity of the AMD Human R2 Polymorphism Factor V (Leiden mutation) assay is up to 100% for Human R2 Polymorphism Factor V (Leiden mutation) mutations under our validation methods and devices.