Factor XIII or fibrin stabilizing factor is an enzyme of the blood coagulation system that crosslinks fibrin. Deficiency of this factor (FXIIID) affects clot stability. Deficiency of Factor XIII leads to defective cross-linking of fibrin and vulnerability to late re-bleeds when the primary haemostatic plug is overwhelmed. Bleeding tendencies similar to haemophiliacs develop, such as hemarthroses and deep tissue bleeding.
Product details:
The assay is an in vitro PCR reaction assay for the Qualitative determination of Human Coagulation Factor XIII in the human sample such as Serum, Plasma and Tissue Homogenate and based on Taqman detection method for Human Coagulation Factor XIII with high sensitive one step qPCR kit.
AMD Human Coagulation Factor XIII kit is very sensitive kit under our validation methods and devices. The specificity of the AMD Human Coagulation Factor XIII kit assay is up to 100% for Human Coagulation Factor XIII DNA.