Human leukocyte antigen (HLA) B27 is a class I surface antigen encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6 which presents antigenic peptides (derived from self and non-self-antigens) to T cells. HLA-B27 is strongly associated with Ankylosing Spondylitis (AS), Pondyloarthropathies (SpA), inflammatory bowel disease, and reactive arthritis.
Product details:
This assay is an in vitro PCR test for the qualitative identification of the HLA-B27 allele in human whole blood samples. It consists of PCR primers specific to HLA-B27 subtypes and a hydrolysis probe for detection in a highly sensitive qPCR master mix.
Quality:
All AMD kits manufactured using high quality standard methods and unique precision, comparable with other leading commercial diagnostic Human Leukocyte Antigen (HLA) B27 kits.
Sensitivity:
AMD Human Leukocyte Antigen (HLA) B27 kit is highly sensitive kit under our validation methods and devices.
Specificity:
AMD Human Leukocyte Antigen (HLA) B27 kit is up to 100% specific for Human Leukocyte Antigen (HLA) B27 under our validation methods and devices.