Solution reagent

for immunoanalysiscTnIcreatine kinase

Diagnose myocardial infarction Evaluate the effect of thrombolytic therapy Evaluation of the scope of re-embolization and embolization Improve early sensitivity and late specificity in the diagnosis of heart disease Performance Characteristics Detection Limit: CK-MB: 2.0 ng/mL; cTnI: 0.1 ng/mL; Myo: 10.0 ng/mL. Linear Range: CK-MB: 2.0-100.0 ng/mL; cTnI: 0.1-50.0 ng/mL; Myo: 10.0-400.0 ng/mL. Linear correlation coefficient R ≥ 0.990; Precision: within batch C.V. is ≤ 15%; between batches C.V. is ≤ 20%; Accuracy: the relative deviation of the measurement results shall not exceed ± 15% when standardized accuracy calibrator is tested. Troponin I is composed of 205 amino acids with a relative molecular weiaht of about 24KD. It is a protein rich in alpha helix; it forms a complex with cTnT and cTnc, and the three have their own structure and function.After myocardial injury occurs in humans, myocardial cells rupture, and troponin I is released into the blood circulatory system, which increases significantly within 4 to 8 hours, reaches a peak value in 12 to 16 hours after myocardial injury, and maintains a high value for 5 to 9 days Troponin I has a high degree of myocardial specificity and sensitivity, and is currently the most idea biomarker of myocardial infarction. Creatine Kinase (CK) has four isoenzyme forms: muscle type (MM), brain type (BB), hybrid type (MB) ano mitochondrial type (MiMi). Creatine kinase is contained in many tissues, but the distribution of each isoenzyme is different. Skeletal muscle is rich in M-type isoenzymes, while brain, stomach, small intestine bladder and lunas mainly contain B-type isoenzymes.