Protein analysis reagent 52007005

for urine samplesfor nephelometrymicroalbuminuria

Intended Use This reagent is intended for in vitro quantitative determination of microalbumin in human urine -Nephelometry methodology -Linear up to 200 mg/L -Ready to use reagents -No need to dilute samples -Lower Detection limit of 5.0 mg/L Clinical Significance Albumin is normally found in the blood. When the kidneys are working properly, albumin will not be present in the urine. However, when the kidneys are damaged, small amounts of al bumin leak into the urine. This condition is called microalbuminuria. Microalbuminuria is most often caused by kidney damage from diabetes. However, many other conditions can lead to kidney damage, such as high blood pressure, heart failure, cirrhosis, or systemic lupus erythematosus (SLE). If early kidney damage is not treated, larger amounts of albumin and protein may leak into the urine. This condition is called macroalbuminuria or proteinuria, this can lead to chronic kidney disease. Principle The reagents containing polyclonal goat antihuman microalbumin when mixed with the urine sample containing microal bumin agglutination occurs which is directly proportional to the concentration of microalbumin in the sample.