1. Laboratory
  2. Laboratory medicine
  3. Blood sample reagent
  4. Agappe Diagnostics Switzerland GmbH

Protein analysis reagent 52007006
blood samplefor nephelometryHbA1c

protein analysis reagent
protein analysis reagent
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Characteristics

Applications
for protein analysis, blood sample, for nephelometry
Tested parameter
HbA1c

Description

Intended Use This reagent is intended for in vitro quantitative determination of HbA1c in human blood. -Nephelometry methodology -Direct result in % HbA1c from analyzer -No total Hb determination required -No calibration required -Linear up to 13% -Lower Detection Limit of 3% Clinical Significance HbA1c is a glycated form of hemoglobin formed by the attachment of glucose residues in the blood to the hemoglobin molecules. In the diabetic population where blood glucose levels are abnormally elevated, the level of HbA1c also increases. The level of HbA1c is proportional to the level of glucose in the blood and has been widely accepted as an indicator of the mean blood glucose concentration in the preceding 6-8 weeks. It is therefore a long-term indicator of diabetic control. For routine use HbA1c levels should be monitored every 3-4 months. Principle The whole blood is lysed using haemolysing reagent. The lysed whole blood containing HbA1c along with other haemoglobins compete to adsorb to the unsensitised latex particles in the R1. A mouse antihuman HbA1c monoclonal antibody is added into the reaction that specifically binds to the human HbA1c molecules to form latex HbA1c- mouse antihuman HbA1c antibody complex. Another antibody, goat anti mouse polyclonal antibody that react with the formed complex to give agglutination. The amount of agglutination is proportional to the amount of HbA1c adsorbed on to the surface of latex particles.

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Meet this supplier at the following exhibition(s):

MEDICA 2024
MEDICA 2024

11-14 Nov 2024 Düsseldorf (Germany) Hall 1 - Stand D04

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