Blood culture assay kit AI-VDFE02

for antigensAspergillusserum

The Aspergillus GM ELISA kit is an immunoenzymatic sandwich microplate assay for the detection of Aspergillus galactomannan antigen in adult and pediatric serum samples and bronchoalveolar lavage (BAL) fluid samples. The Aspergillus GM ELISA kit is a test which, when used in conjunction with other diagnostic procedures such as microbiological culture, histological examination of biopsy samples and radiographic evidence can be used as an aid in the diagnosis of Invasive Aspergillosis. 2-SUMMARY AND EXPLANATION Aspergillus infections usually start in the lung as the port of entry following inhalation of Aspergillus spores which are present in the environment. Invasive forms, which have been on the increase for the past 10 years, constitute the most serious infections. They mainly occur in immunocompromised patients, such as acute leukemia, bone marrow stem cell transplantation, solid organ transplantation, and malignant tumor chemotherapy. The incidence of clinically IA has been on the rise over the past few decades as the number of patients with immunodeficiency, transplantation or high dose hormone therapy has increased. Aspergillus is rarely isolated from blood culture. The diagnosis is often based on nonspecific diagnostic or radiological evidence (clinical symptoms, CT scan, chest x-ray, etc.) The test for soluble galactomannan antigen in serum appears to be a serological method able to aid in the diagnosis of Invasive Aspergillosis. 3-PRINCIPLE OF THE PROCEDURE The Aspergillus GM ELISA kit is a immunoenzymatic sandwich microplate assay which detects galactomannan in human serum and BAL fluid.