The Adenosine HPLC is for Research Use Only and not for use in diagnostic procedures.
Specifications
Regulatory Status
Research Use Only. Not for Use in Diagnostic Procedures.
Product Distribution
Available in North America Only
Range
0.78 - 6.84 µM
Sensitivity
0.78 µM
Sizes
Other
Size Other
48 tests
Inc Time Minute
30
Inc Time Overnight
No
Inc Time See Protocol
No
Additional Information
Adenosine is a ubiquitous, biologically important nucleoside which is a precursor of other biologically active molecules as well as a component of some co-factors. Moreover, it also has its own distinct physiological functions in the central nervous system, the cardiovascular system, the skeletal muscle and the immune system. One of the principal intracellular actions of adenosine is inhibition of the enzyme phosphodiesterase. Extracellular adenosine has specific neuromodulatory actions on dopamine and glutamate.
Adenosine can act either as a hormone by binding to adenosine receptors or as an intracellular modulator after its translocation into the cell by membrane transport proteins. Four adenosine receptor subtypes have been identified. Notably, adenosine receptors are most widely expressed in the brain and the cardiovascular system, but they also are found in the most of the other tissues: respiratory tract, intestine, kidney, skeletal muscle, pituitary gland, uterus and gonads. Adenosine modulates several physiological effects by stimulating specific cell surface receptors.