Microplate scanner SUPR-DSF

fluorescencecompact

The SUPR-DSF by Protein Stable delivers next level differential scanning fluorimetry by simplifying sample preparation and analysis of protein stability into a single microplate. Utilising precision optical components to deliver the highest sensitivity, intrinsic fluorescence of proteins and full spectrum detection, both thermal ramping and isothermal chemical denaturation experiments can be easily run in 384-well microplates. TECHNOLOGY High throughput thermal ramping stability screening Intrinsic fluorescence - broad compatibility with biological buffers Fast, 384-well plates scanned at 1oC per minute Wide dynamic range of sample concentrations Very low protein requirement and volumes needed APPLICATIONS Formulation and buffer optimisation Protein characterisation Stability profiling Similarity assessment Accelerated stress and forced degradation studies Binding-induced conformational changes analysis Post-translational modification assessment FEATURES Next generation differential scanning flourimetry EASE OF USE IS AT ITS CORE The SUPR-DSF was designed specifically to deliver great protein stability screening whilst simplifying processes, thus reducing operator time in preparing samples, reducing the amount and cost of consumables required, and reducing the risk of errors in extra preparation steps. By developing a system that can read directly in-plate, the shift in intrinsic fluorescence of protein samples as they unfold, Protein Stable has eliminated several steps seen in other techniques.