Automatic filling machine Crystal™ M1

benchtopR&Daseptic

The Crystal™ M1 Filling Station is a tabletop aseptic filling system, de-risking your manual fill & finish operation. The Crystal™ M1 Filling Station operates with the AT-Closed Vial®, remaining functionally closed throughout the filling process, significantly reducing the contamination risks typically associated with the manual fill & finish. The system consists of the filling unit with its dosing system, precision balance, laser re-sealing unit and a capping tool. Installed in a Biosafety Cabinet or an isolator, the system provides flexibility and ease of switch to the AT-Closed Vial® technology. Features 0,1 ml to 50 ml filling At your site in 6 weeks Installed and qualified in 1 day Easy validation For standard biosafety cabinet High filling accuracy Single-use material only Toolless format change Reproducible scalable process Perfect for Crystal™ M1 Filling Station addresses the needs of the small and personnalized batches processing. It is widely used for cGMP Manufacturing, Process Development and R&D activities. Functioning principle Using the M1 Filling Station, the AT-Closed Vial® are individually filled through the stopper, laser re-sealed and capped, while being manually transferred between the process stations within the critical area. To prepare the batch, the bulk product is connected to the AT-Filling Kit™, the dosing system and laser control unit are calibrated.For practical and ergonomic process, the AT-Closed Vial® can be provided in AT-CryoBox™, accompanied with AT-Cap™ in rigid support. One by one, the vials are installed on the base of the filling tool.