The QuantideX® qPCR BCR-ABL minor Kit (RUO) is a clinical research tool enabling ultra-sensitive and precise detection of BCR-ABL1 minor fusion transcripts (e1a2) from whole blood specimens. Building on the simple workflow and best-in-class sensitivity established with the FDA-cleared QuantideX® qPCR BCR-ABL IS Kit, the minor Kit allows labs and clinical researchers to examine the biology of disease for this very rare but distinct leukemic variant with unprecedented ease.
Features & Benefits
The QuantideX qPCR BCR-ABL minor Kit (RUO) delivers high performance through unmatched sensitivity and optimized laboratory efficiency.
Reduced Complexity
Ease-of-data analysis and reporting:
Leverages the QuantideX® qPCR BCR-ABL IS Kit workflow concept for streamlined implementation
QuantideX qPCR Reporter provides automated calculation of BCR-ABL1/ABL1 % ratio and eliminates the need for manual calculation
Optimized Workflow
Valuable operator hands-on time has been significantly reduced through:
Multiplexed design amplifies and detects both fusion and control gene in the same reaction
All-inclusive reagents sourced and quality controlled together from a single vendor
Pre-mixed reagents allow fewer pipetting steps in mastermix preparation
Quality Performance
Detecting BCR-ABL1 minor transcripts robustly and reliably with a highly sensitive assay:
Ultra-sensitive Limit of Detection (LOD): Log reduction of 4.61 (0.0025% ratio)
Increased analytical sensitivity without compromising analytical specificity: incorporates Limit of Blank (LOB) to prevent miscalling of non-leukemic low positives
Armored RNA®-based standards provide true RNA quantification