Automatic molecular screening system ICR 12000

for drug discoverymedium throughput

The ICR 12000 is designed for ultra-high throughput ion channel screening of compound libraries, incorporating multi-channel sampling and enhanced automation features. Based upon the versatility, precision, and sensitivity of Aurora Biomed’s atomic absorption spectroscopy (AAS) instruments, the ICR 12000 is suitable for both ligand-gated and voltage-gated ion channels using cell-based flux assays. With the robustness of Aurora Biomed’s ICR technology, the reader offers high sensitivity for both electrogenic and electroneutral channels and transporters. The incredible 60,000 sample per day throughput of the ICR 12000 enables ion channel researchers to access compound QT liability early in the drug discovery process. Specifications Minimum sample volume: 20 µl Accommodation: 96/384-well microplates Footprint: H.120 cm X W.95 cm X D.37 cm Fuel Source: Acetylene / Compressed Air Options: Plate Stacker / Barcode Reader Sensitivity: 0.05 ppm detection limitPrecision: < 5% CV Features & Benefits Programmable and automated solution for up to 60,000 wells/day Automatic dilution, calibration and cleaning Integrated plate stacker & bar code reader Sample dilution not required High sensitivity On-line dilution Eliminates quenching effects associated with fluorescence Removes need to work with hazardous radioisotopes Avoids work restrictions posed by Rb’s short half-life Ideal for hERG channel assays Can assess both electrogenic and electroneutral transporters