Nerve tissue matrix avance®

allograft

Avance Nerve Graft is the only off-the-shelf biologically active processed human nerve allograft intended for the surgical repair of peripheral nerve discontinuities. avance innovations Organized, linear and continuous structural support for cellular migration and regenerating axons. Clinically proven, off-the-shelf solution with 82% meaningful recovery in sensory, mixed and motor nerve gaps up to 70 mm. Proprietary cleansing, decellularizing and sterilizing methods specifically designed to maintain both the natural nerve structure and biological activity of native nerve. Intra-operative versatility to meet a range of anatomical needs. preferred choice Avance Nerve Graft is the preferred choice in digital nerve repair over conduit, autograft or vein graft.* *Results of a survey of 461 hand surgeons with their method for repairing a 2 cm digital nerve gap 82% meaningful recovery rate, defined as Medical Research Council Scale of S3/M3 or greater, throughout the body after reconstruction. 14+ years of unrivaled expertise in nerve tissue recovery. the avance method™ The Avance Method is Axogen’s proprietary methodology for recovering, cleansing, sterilizing and ensuring quality of the Avance® Nerve Graft. This establishes Avance Nerve Graft as the most effective, natural alternative to a patient’s own tissue preserved architecture Preserves the delicate 3D macro- and micro-architecture of native nerve, which provides structural support for the regenerating axons. bioactive laminin Enzyme treated to inactivate the inhibitory aspects of chondroitin sulfate proteoglycans (CSPGs) exposing laminin, which is known to promote nerve regeneration.