Nerve tissue matrix axoguard®

Axoguard Nerve Protector is the only small intestine submucosa (SIS) implant designed to protect injured and compressed nerves up to 40 mm. protector innovations Provides a protective barrier to separate the nerve from the surrounding tissues. Minimizes the potential for soft tissue attachments to allow the nerve to glide. Vascularizes and remodels into the patient’s own tissue. Available in a variety of lengths and diameters for intra-operative versatility. the importance of biomaterials In a pre-clinical study conducted to evaluate host tissue response, porcine small intestine submucosa (SIS, Axoguard Nerve Connector) performed significantly better than cross-linked bovine collagen type I (CLC, Integra NeuraGen®) in all outcomes and categories. Specifically, the study provided evidence that SIS had increased levels of M2 (pro-healing) macrophages which are indicative of a remodeling response, while CLC had increased levels of M1 (pro-inflammatory) macrophages indicative of a chronic inflammatory response indications for use INDICATIONS FOR USE: Axoguard Nerve Protector is indicated for the repair of peripheral nerve injuries where there is no gap. The device is supplied sterile and is intended for one-time use. CONTRAINDICATIONS: This device is derived from porcine source and should not be used for patients with known sensitivity to porcine material.