Genetic mutation assay kit

cellfluorescence

Stratagene Mx3000P, ABI 7300Plus, ABI 7500, Shanghai Hongshi SLAN-96S Product Descripption Adopting the ARMS-PCR method, this kit completely covers 45 drug susceptibility and resistance mutations in EGFR exons 18-21, and is presently one of the EGFR gene mutation detection kits involving the most comprehensive detection loci for fluorescent quantitative PCR in the market. This kit is used for qualitative assay of human epidermal growth factor receptors (EGFR) gene mutations in patients with non-small cell lung cancer (NSCLC). The product contains our proprietary stabilizer with which high specificity can be guaranteed and false positives can be avoided under the situation when the sensitivity reaches 1%. The assay result can be used as the reference for clinicians’ selection of population who may receive iressa (gefitinib), tarceva (erlotinib), conmana (icotinib) and other targeted drugs among NSCLC patients. The product can be used in in vitro tests only. The assay result can only be used for clinical reference and shall not be used as the only basis for diagnosis and treatment. Product Features High selectivity——Detect as low as 1% of mutations in 5 ng] DNA from multiple types of samples High sensitivity——Only a few hundred copies are needed to detect the target gene High specificity——The amplification curve is flattening when wild type samples are tested Easy to operate—— Pre-assembled to facilitate standard operation in the lab Convenient and fast——Suitable for various PCR instruments, test completed in 90 minutes Stable and reliable——Closed tube reaction, IR-IC dual QC to avoid false negatives and positives