Stratagene Mx3000P
Product description
Adopting the ARMS-PCR method, this kit can be used to detect 9 EML4-ALK fusion genes, about mor than 90% of EML4-ALK fusion genes.
This kit is used for qualitative assay of 9 EML4-ALK fusion genes in patients with non-small cell lung cancer (NSCLC). The product contains our proprietary stabilizer with which high specificity can be guaranteed and false positives can be avoided under the situation when the sensitivity reaches 1%. The assay result can be used as the reference for selection of population who may receive xalkori (crizotinib and other small-molecule inhibitors of ALK among NSCLC patients. The product can be used in in vitre tests only. The assay result can only be used for clinical reference and shall not be used as the only basi for diagnosis and treatment.
Product Features
High selectivity——Detect as low as 1% of mutations in 5 ng] DNA from multiple types of samples
High sensitivity——Only a few hundred copies are needed to detect the target gene
High specificity The amplification curve is flattening when wild type samples are tested
Easy to operate—— Pre-assembled to facilitate standard operation in the lab
Convenient and fast——Suitable for various PCR instruments, test completed in 90 minutes
Stable and reliable——Closed tube reaction, IR-IC dual QC to avoid false negatives and positives
Convenient read-out——No non-specific amplification, read the result directly, no need to manually calculate the =CT value