Cancer assay kit

oncologyfor KRAS mutationscell

Applicable instrument Stratagene Mx3000P, ABI 7500. Roche LC480, Abbott m2000rt, BioRad CFX-96 Product Description Adopting the ARMS-PCR method, this kit can be used to detect 7 hot-spot mutations in codons 12 and 13 of exon 2 of the KRAS gene, about more than 95% of known mutation loci in clinical research. This kit is used for qualitative assay of mutations in the KRAS gene of human patients with non-small cell tung cancer (NSCLC) and colorectal cancer. The product contains our proprietary stabilizer with which high specificity can be guaranteed and false positives can be avoided under the situation when the sensitivity reaches 1%. The assay result can be used as the reference for clinicians’ selection of population who may receive anti-EGFRs (targeted drugs) among patients with NSCLC and colorectal cancer. The product can be used in in vitro tests only. Product Features High selectivity——Detect as low as 1% of mutations in 5 ng‘ DNA from multiple types of samples High sensitivity——Only a few hundred copies are needed to detect the target gene High specificity The amplification curve is flattening when wild type samples are tested Easy to operate—— Pre-assembled to facilitate standard operation in the lab Convenient and fast——Suitable for various PCR instruments, test completed in 90 minutes Stable and reliable——Closed tube reaction, IR-IC dual QC to avoid false negatives and positives Convenient read-out——No non-specific amplification, read the result directly, no need to manually calculate the “CT value Worry-free after-sales service——Instant response, comprehensive after-sales service