Cardiovascular disease test kit 0009HC

D-dimerplasmawhole blood

Product Name: D-dimer detection kit （Magnetic Solid Phase Chemiluminescent Immunoassay） Packaging: 24 T/KIT Intended Use: This product is used for the in vitro quantification of D-Dimer in human plasma and whole blood. D-Dimer is a specific marker of the fibrinolytic process that is produced by cross-linking of fibrin monomers by activator XIII and then hydrolysis by fibrinolytic enzymes. The fibrinolytic system is the most important anticoagulant system in the body and consists of four major components: fibrinogen, fibrinogen activator, fibrinolytic enzymes, and fibrinase inhibitors. When fibrin clots are formed, fibrinogen activation is converted into fibrinolytic enzymes in the presence of fibrinogen activator, and the fibrinolytic process begins. Both X-oligomers and D-dimers contain D-dimer units. D-dimer mainly reflects fibrinolytic function. Increased or positive D-dimer is seen in secondary hyperfibrinolytic conditions such as hypercoagulability, diffuse intravascular coagulation, renal disease, organ transplant rejection, and thrombolytic therapy. Whenever there is activated thrombus formation and fibrinolytic activity in the body's blood vessels, D-dimer will be elevated. Myocardial infarction, cerebral infarction, pulmonary embolism, venous thrombosis, surgery, tumors, diffuse intravascular coagulation, infection, and tissue necrosis can all lead to elevated D-dimer. Especially in the elderly and inpatients, the disease such as bacteraemia may cause abnormal coagulation and lead to elevated D-dimer.