Gastrointestinal disease test kit 00032C

pepsinogen Iserumplasma

Product Name: Pepsinogen I/Pepsinogen Ⅱ (PGI/PGII) Test Kit (Immunofluorescence) Pepsinogen I and II, the precursors of pepsin, are produced by the gastric mucosa and released into the gastric lumen and peripheral circulation (Samloff and Liebman, 1973). Severe inflammation of gastric mucosa and its progression toward atrophic gastritis (AG) is correlated with a change in serum biomarkers pepsinogen I and II. It has been previously reported that pepsinogen II is a good marker for the diagnosis of any type of gastritis as it can differentiate between subjects with gastritis from those with normal mucosa. The progression of gastritis to acute and pangastritis is associated with a continual increase in serum pepsinogen II levels, whereas the levels of pepsinogen I in the early stage of acute gastritis remain unchanged and in the normal range. Sample type WB/S/P Sample vol. 75 μL Working range PGI: 10-200ng/mL PGII: 5-100ng/mL Performance CV≦15% Storage 2-30℃ Shelf Life 18 months