Heart fatty-acid binding protein (H-FABP) is one of the most abundant proteins in cardiomyocytes. Upon acute myocardial infarction (AMI) the blood and urine levels of H-FABP rise rapidly within 1-3 hours, reach their peak values at 6 hours, and return to baseline concentration within 24 hours. Characteristics of H-FABP appear to be similar to those of myoglobin. However, H-FABP concentrations are almost 10-fold higher in the heart than in the skeletal muscle. In contrast, myoglobin concentrations are 2-fold lower in cardiac cells than skeletal cells. Thus, the greater cardiospecificity of H-FABP account for its greater value in diagnostics of AMI.
Sample vol.
75μL
Working range
1-100 ng/mL
Performance
CV≦15%
Storage
2-30℃
Shelf Life
18 months