Solution reagent kit AccuTarget™

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AccuTarget ™ miRNA Housekeeping Positive Control targets the 3 'UTR (untranslated region) of GAPDH, a widely used human housekeeping gene. Features and Benefits Ready-to-transfect miRNA mimic Same activity as the endogenous miRNA actually present in the cell after transfection Wide Applications miRNA inhibitors for studying the loss-of-function of miRNAs by inhibiting the activity of target miRNAs Overview • What is MicroRNA? MicroRNAs (miRNAs) are 21-25 nucleotide(nt) single-stranded RNA molecules that act as post-transcriptional regulators for eukaryotic gene expression. miRNA works by binding to the 3’UTR (untranslated region) of the target mRNA to make it unstable, resulting in inhibition in translation and protein synthesis. As process is one of the most crucial step in many biological processes such as development, cell proliferation, differentiation, apoptosis and metabolism, about 2,000 miRNA are expressed in the human human genome. • AccuTarget ™ Human miRNA mimics & inhibitors - AccuTarget ™ miRNA mimic is a chemically synthesized double-stranded RNA oligonucleotide. - The miRNA mimic for this product is synthesized for human mature microRNA based on the latest version of miRBase Sequence Database (Ver. 22). - AccuTarget ™ miRNA inhibitor are single-stranded synthetic inhibitors having complementary sequences to target human microRNAs. ▶ Specifications miRNA mimic and inhibitor can be ordered from the following: 5, 10, or 20 nmol guaranteed yields A library set composed of predesigned miRNA mimics or inhibitors of various sizes (0.25, 0.5, 1, 2 nmole) is provided on a 96-well plate.