Selective stimulation of small intradermal nociceptive fibers by electrical impulse
Description
The μPatterned Electrodes, thanks to their interdigitated design together with micrometric inter-rail gap, allow the delivery of a shallow but effective electrical stimulation limited to the epidermis, selectively activating the Aδ fibres, while avoiding costimulation of the deeper Aß fibres[1][2].
By using the μPatterned Electrodes it is then possible to objectively assess the conduction along the nociceptive pathway by recording from the peripheral nerve or from the scalp overlying the sensory cortex (nociceptive Evoked Potentials, or NEPs) [3], [4].
Of course the recording of classical endogenous responses called Pain Related Evoked Potentials (PREPs) is still possible with the same electrodes.