Oxidative stress assay kit KB03002

lipidmalondialdehydefor molecular biology

Lipid peroxidation (LPO) is a well-known example of oxidative damage in cell membranes, lipoproteins, and other lipid-containing molecules in conditions with oxidative stress. Lipid peroxidation may contribute to the pathology of many diseases including cardiovascular diseases, cancer, and neurodegenerative diseases. Non-enzymatic LPO is a complex process whereby polyunsaturated lipids are oxidized via free-radical intermediates to a variety of products. Briefly, unsaturated fatty acids react with molecular oxygen via a free radical mechanism producing hydroperoxides. These primary products of lipid oxidation are highly unstable and rapidly decompose resulting in the formation of secondary compounds such as aldehydes, ketones, alkanes, carboxylic acids, and polymerization products. These secondary products are also highly reactive with other cellular components /extracellular matrix and can be used as biomarkers for LPO. Additional information Sizes: 100,200 and 400 tests Expiry date: 1 year Storage: 4ºC and room temperature Reagents: LPO solvent, Reagent A, Reagent B, and Standard (1,1,3,3-tetrametoxipropano) Necessary material: 96 well-plate spectrophotometer