The advanced version of our Dynamic Weight Bearing Test allows for faster paw identification, based on a video solution taking advantage of the most advanced algorithms of morphologic analysis in dynamic conditions. An efficient and advanced alternative to traditional incapacitance tests for assessing pain sensitivity in your research on analgesia/nociception involving rats and mice, including work on ostheoarthritis, bone cancer, analgesic substances, Parkinson disease, allodynia...
Presentation
Ethical considerations as well as the necessity to study comfort and non-evoked pain levels on rodents lead to the development of tests and procedures allowing researchers to conduct pain assessment without having to apply a stimulus on the animals. These tests, called 'Incapacitance' tests, measure the weight distribution on both hind paws of rodents maintained in a restrainer. Restraining, however, induced higher level of stress for the test subjects.
Since its launching in 2008, Bioseb's Dynamic Weight Bearing test is the only rodent non-evoked pain test not requiring animal restraint. It is also the only instrument allowing you to precisely measure changes in Postural Equilibrium in rodents by assessing their weight distribution on each one of their 4 paws.
Bioseb's DBW thus allows you to work with freely moving animals in a transparent cage adapted to the animal being tested (rats or mice). This unique characteristic significantly reduces restrainer-induced stress levels and therefore greatly increases the reliability of the results.