Von Frey analgesiometer BIO-EVF5

for animal researchfor micefor rats

The latest evolution of Bioseb's Electronic Von Frey instrument for determining the mechanical sensitivity threshold in rodents (rats and mice). The EVF5 includes an embedded camera inside the stimulator handle and a new, dedicated software revolutionizing the experimental process. 16 years after the creation of our first Electronic Von Frey instrument, Bioseb is revolutionizing this standard test for determining the mechanical sensitivity threshold in rodents (rats and mice). A well-known issue with classical Electronic Von Frey instruments is the necessity for the operator to bend into an uncomfortable posture in order to stimulate under the rodents' paws. Despite using more ergonomic workplace configurations (lower seats and elevated desks), the operation can remain strenuous or even painful for the operator when repeated over large cohorts of animals. In order to solve this issue, we embedded a camera inside the stimulator handle, which allows you to record and display video directly from underneath the paws. In conjunction with our dedicated software, this innovation allowed us to re-think the position of the operator during the test. When used on a tablet or touch-screen, the EVF5 software allows operators to visualize the video stream in real time without having to bend over. Furthermore, it integrates all additional functionalities that might be required during such a test: • Animal lists management. • Real-time curves display: visualizing the force over time helps operators improve their execution and the repeatability of their measurement • A table allowing you to assign each measurement to the corresponding paw by directly clicking on the touch screen.