Automated ladder test BIO-LADDERTEST

gaitlocomotionfor medical research

Fully automated instrument for sophisticated detection and analysis of foot faults on the horizontal ladder test for investigation of walking disorders, motor coordination and motor learning. BIOSEB innovated the traditional foot misplacement instrument with synchronized beam break and video detection to assign errors with anatomic precision. Presentation A horizontal ladder test is commonly used to assess the walking capability of mice and rats, and their motor-function using both forelimbs and hindlimbs in a coordinated pattern. Applications in neurodegenerative studies, as well as Spinal cord injury, osteoarthritis and ischemia/stroke models are increasing. To achieve research goals, investigators are in need of accurate instruments that precisely measure loss or gain of function in compromised animals and during recovery. With the Automatic BIO-LADDERTEST, Bioseb now offers the perfect tool to measure rodent walking skills in an automatic way! Based on our existing Foot-Misplacement Apparatus, the Automatic Ladder Test packages easy-to-use software, video tracking camera, and a comfortable elevated frame with the enclosed adaptive ladder for the most sensitive and comprehensive solution for evaluating skilled walking in mice and rats. Operating principles The horizontal ladder is constructed of a Plexiglas corridor with removable plastic rungs that are inserted with a regular spacing to create a floor. The purpose of the test is to access the foot “faults” (misplacement of the limbs between 2 rungs) made by the animal while traversing the corridor.