Tail suspension test animal research cage BIO-TST5

modular

Bioseb's version 5 of the Tail Suspension Test system, based on both strain sensors and video acquisition, is the only fully automatic solution in the world for running a simple and objective despair test on mice. It is a fast, painless, and reliable way for testing psychotropic effects from stimulant doses of drugs such as anti-depressants and sedatives. This classic and painless research test for anxiety and depression is now offered with a new, powerful and modern software, in a wireless, bluetooth-based version. The tail-suspension test was developed as an alternative to the Porsolt Forced Swimming test, and is based on a similar concept. Mice, suspended by their tail using a piece of tape (a painless method), innately attempt to escape from this adversive situation. However, following failed attempts to escape, they experience a kind of despair and become immobile. The magnitude of immobility is considered to be correlated with the depressive-like state of the subjects and is significantly decreased by antidepressants. The Tail Suspension Test was described in the 80's by Steru & al. and allows for fast evaluation of drugs' (anti-depressants, sedatives) psychotropic effects, making it a classic and painless research test for anxiety and depression. BIOSEB' Tail Suspension Test system is the only full automatic test in the world!. It is based on the original “ITEMATIC-TST” described by Steru in 1987, it uses both strain gauges and video backup recording, and does not induce any pain in the animal: the mouse’s tail is simply stuck to the sensor using a piece of tape.