Tabletop vital signs monitor BP-2000

heart rateNIBPfor animal research

The world's leading non-invasive blood pressure analyzer for mice and rats: a state-of-the-art, expandable instrument based on transmission photoplethysmography, highly accurate and reliable for measurements on animals ranging from small mice to extremely large rats. Comes with a powerful, yet intuitive, dedicated software to review and verify your data, and export your results. OPERATING PRINCIPLES The BP-2000 uses transmission photoplethysmography, in which variations in the amount of light transmitted through the tail is the basic signal that is analyzed to determine the blood pressure and pulse rate. Every time the heart beats, a pressure wave travels through the vascular system. When it reaches the tail, the vessels dilate slightly, and thus scatter more red light. (This corresponds to systole.) As the pressure wave passes, the vessels in the tail get smaller as the pressure decreases, and less light is scattered. (This corresponds to diastole.) The variation in light transmitted through the tail is what the BP-2000 displays on the computer screen. Photoplethysmography is very effective at measuring blood pressure on animals ranging from small mice to extremely large rats. And unlike approaches that use an additional sensing cuff (or volume-pressure cuff), photoplethysmography works more reliably with small mouse tails (and does not require two cuffs on the tail). The diastolic and systolic pressure can be determined by monitoring the vessel dilation as the occlusion cuffs inflates. Here is a plot of actual data showing where diastolic and systolic are measured: PARAMETERS MEASURED Pulse disastolic sistolic mean pressure standard deviation