he world’s first and only laser-based microplate nephelometer was developed to meet high-throughput demands for fast compound solubility screens. The NEPHELOstar® Plus detects insoluble particles in liquid samples by measuring forward scattered light and can be used for turbidity measurements, drug solubility screening, protein binding kinetics, microbial growth, and petroleum process control.
The NEPHELOstar Plus is a microplate nephelometer with a high-intensity laser diode. It can be up to thirty times more sensitive than traditional transmission optical density readers that measure the reduction in direct light passing through a sample well. Thanks to its speed, flexibility, and performance, the NEPHELOstar Plus allows more applications to be adapted to microplate-based laser nephelometry than ever before.
Features
Adjustable laser intensity and beam diameter
Measurement in up to 384-well microplate format
Incubation up to 45°C or 60°C
Linear, orbital and double-orbital shaking
High-precision injectors with simultaneous reagent injection and detection
Microplate Stacker and robot compatible
Easily integrated into automated systems
Application notes
Improving throughput for assessing nephelometric turbidity units (NTUs) using the NEPHELOstar® Plus
Nephelometric turbidity units (NTUs) refer to the concentration of particles to describe the quality of water. Read how the NEPHELOstar® Plus microplate nephelometer determines NTUs in low sample volume.
Nephelometric monitoring growth of Candida albicans using BMG LABTECH's NEPHELOstar Plus
Laser nephelometry was used for the rapid determination of the solubility of potential antimycotic drug compounds