It’s used to select mature and superior sperms for ICSI. It is safe and noninvasive. Have more advantages in technology than traditional PVP method.
BreDevice® HA-ICSI, a sterile device with solid hyaluronic acid pre-coated in the center hole of the culture dish, is used for the selection and separation of sparing mature sperms.
The mature sperms, having capability of mobile and hyaluronic acid binding sites on the surface of sperm head, could bind with solid hyaluronic acid precoated in the center hole of the culture dish.
However, the immature sperms could not bind with hyoluronic acid because such sperms don’t have hyaluronic acid binding sites on the surface of sperm head. Then the mature sperms could be selected for ICSI.
Feactures:
1. The DNA of selective sperm would be more intact
2. The morphology of selective sperm would be better.
3. The chromatic abnormality of selective sperm would be reduced 4-6 times in rate.
4. The immature neucleoprotein of selective sperms would be less. The volume of CK-B, HspA2 would be remarkable higher.
5. Combined with the kit for sperm-hyaluronic acid binding assay, pregnancy loss rate would be reduced significantly.
6.Combined with the kit for sperm-hyaluronic acid binding assay, clinic pregnancy rate (CPR) would be improved greatly.