The fully automated DBS-MS 500 HCT from CAMAG contains state-of-the-art technology to analyze target substances out of a DBS (Dried Blood Spot) on a DBS card. The DBS is directly eluted in the extraction chamber and the analytes are guided online to the analytical system of choice or the extract is collected into a vial or 96 well plate. Sample processing is automated, including the application of an internal standard through a high-precision sprayer, detecting the sample's hematocrit through an optical module, and a barcode assignment from the DBS card. In addition to the analytical results, a picture of each DBS card before and after extraction and the run parameters are reported to maintain full traceability and the highest quality.
Key features:
- High-throughput analysis of up to 500 DBS cards per run
- Integrated optical card recognition and barcode reading module
- Non-destructive hematocrit detection through an optical module
- Automated internal standard application module
- Unique extraction module with wash station to eliminate carry-over
- Online coupling to the analytical system (MS or LC-MS)
- Full control through Chronos software
The fully automated CAMAG DBS-MS extraction system makes DBS analysis remarkably easy and has strong advantages compared to both, the manual and semi-automated punching techniques. With the CAMAG DBS-MS 500 HCT extraction procedure, DBS analysis is an economical alternative to conventional blood sampling. It represents a time- and cost-saving technique to analyze pharmacological samples, and is less invasive for participants or animals.