Staining solution reagent kit SD9001

antibodystainfor research

P16/Ki-67 dual staining detection reagent kit (immunocytochemistry) is an detection reagent for cervical cell screening shunt and diagnosis of cervical tissue samples. It adopts immunohistochemical double-staining detection and multi-antibody combination technology. Two antigen targets, p16 and Ki-97, can be detected simultaneously on the same sample tissue section by one staining process. The p16 gene has the function of inhibiting cell proliferation during the cell cycle arrest period and is strongly expressed in cervical intraepithelial neoplasia and cervical cancer, which is an objective biomarker for cervical lesions. Ki-67 is a biomarker of cell proliferation, and its overexpression indicates that the cell is in the proliferation phase. Normally, the expressions of p16 and Ki-67 are mutually exclusive. The co-expression of p16 and Ki-67 indicates that the cell cycle is disordered and the cells continue to proliferate. p16 alone as the identification standard is required combining morphology and detected simultaneously with Ki67. The results are more reliable. Product Features Application Combined screening with Liquid-based cytology + HPV + immunohistochemistry double staining As a shunt detection measure for ASC-US and LSIL For shunting samples with normal cytology/positive HPV test Shunt high-risk HPV-positive patients except HPV16/18 on HPV primary screen