1. In more than 90% of Ewing's sarcoma patients (more than 20 years old), the EWSR1 gene may be split and fused with multiple genes such as FLI1 gene fusion (85%) and ERG gene fusion (10%).
2. It is used for auxiliary diagnosis of Ewing's sarcoma, as well as mucinous liposarcoma, connective tissue hyperplastic small round cell tumor, hemangioma-like fibrous histiocytoma, clear cell sarcoma and extraosseous mucinous chondrosarcoma.