1. IGH gene breakapart and translocation are complex, involving multiple genes, and are commonly found in ALL ,MM and lymphoma.
2.It can be used to detect whether IGH gene is abnormal or small residual lesions
3. IGH gene fragmentation can be used as a marker of malignant cloning of myeloma cells, which is not affected by clinical stage or immune type, and can be used as one of the favorable bases for MM diagnosis.