CD79 a is encoded by the mb-1 gene, formerly known as Ig α. The antibody recognizes an extracellular site expressed on the CD79 molecule and detects all b-cell tumors in routine biopsy material. In addition to being expressed in B cells, CD79a was also found to be co-expressed with CD3 in 10% of T lymphoblastic leukemia/lymphoma cases. CD79a antibody may also be useful in differential diagnosis of Hodgkin's disease.
Staining Tissue
As Figure shows:
Tonsil tissue stained with CD79a