C4D is a stable component that is covalently bound to endothelial cells and basement membrane, and the main production pathway is classical antibody-induced complement activation.This component can be detected in chronic rejection of kidney transplantation, hyperacute rejection, acute vascular rejection, acute cellular rejection and borderline rejection, and it is an indicator for the treatment of acute rejection.
Staining Tissue
As Figure Shows:
Renal tissue stained with C4d