The (1,3)-b-D glucan molecules can be found in the cell walls of most yeasts and molds. These glucans contaminate cell culture fluid, yeast protein production, air quality samples, and cellulose filter preparations. Allow us to help you ensure that your product is free of glucans and isn’t triggering false-positive results in the LAL test leading to potential investigations.
Rapid beta-D-Glucan Detection
With recent inspections indicating a need to verify the absence of glucans, the assurance that your product is free of contamination is essential. Endosafe® beta-glucan cartridges provide a rapid, in-process test designed for investigational purposes to ensure that products do not contain (1,3)-β-D glucans. This allows you to quantify glucans faster and easily, leading to better process monitoring and faster out-of-specification (OOS) resolutions.
Features
Employs the Limulus enzyme cascade to detect the presence of (1,3)-b-D glucan
Interfaces with our suite of scalable, automated Endosafe cartridge technology platforms
Designed to mimic kinetic chromogenic methods by measuring color intensity directly related to the (1,3)-b-D glucan concentration
Each cartridge contains precise amounts of glucan-specific LAL formulation, chromogenic substrate, and glucan standard
Sensitivity range of 10-1,000 pg/mL
Applications
LAL endotoxin OOS results
Yeast protein production
Cell culture fluid
Air quality
Cellulose filter preparation
Test Procedure
Pipette 25 μL of a sample into each of the four sample reservoirs of the cartridge
Insert the cartridge into a Endosafe cartridge technology platform and press begin the test