Introducing the world’s first IgY based CHO-HCP ELISA kit specifically designed to close the detection gaps in your impurity testing. By leveraging our extensive in-house experience and comprehensive end-to-end solutions, we’ve developed and patented a novel HCP kit capable of detecting up to 90% of the HCP proteins present in the sample.
What Makes IgY Antibodies an Attractive Alternative for CHO-HCP ELISA Kits
In contrast to other commercially available mammalian IgG based host-cell protein kits, our CHO-HCP ELISA kit leverages the avian IgY antibody, specifically, those found in specific pathogen free (SPF) chickens, as the primary detection technology and is capable of detecting up to 90% of the HCP proteins present in the sample.
What makes IgY antibodies an attractive alternative to IgG is due in large part to the phylogenetic distance between avians and mammals. The avian IgY antibodies used in our CHO-Host Cell Protein kit recognize mammalian antigens as highly foreign, which produces an aggressive immune response that far exceeds those of other commercially available IgG HCP kits.
The Benefits of Using IgY vs IgG in Diagnostic Applications
Chicken immunoglobulin Y (IgY) is a highly conserved homolog of human immunoglobulin G (IgG) that has shown benefits and a favorable safety profile, primarily in animal models of human infectious diseases.
Compared to IgG, IgY antibodies:
Are easy to produce
Can be generated economically in large quantities
Are more environmentally friendly
Require less infrastructure investment by using egg-laying hens (1)
Partnership and Development Opportunities for HCP KitsAre you tired of running into coverage GAPs?