Endotoxin testing laboratory automation system Endosafe® Nexus 200™

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Built for GMP environments, the Endosafe® Nexus 200™ automates endotoxin testing by removing repetitive, error-prone steps that slow you down and increase the risk of retests. Shift your focus to interpreting data and maintaining process control. Instead of managing the instrument, concentrate on what matters, ensuring product quality and compliance. The Challenge with Manual and Semi-Automated Testing Even in large-scale labs, many BET workflows still rely on manual or semi-automated processes: Analysts prepare standard curves, serial dilutions, and reagents by hand Sample transfers introduce variability and transcription errors Extended training is required before staff reach proficiency These steps create bottlenecks, higher retest rates, and delays that affect product release. In regulated environments, a single invalid run can lead to reprocessing, wasted consumables, and compliance findings. They also drive out-of-specification investigations and tie up skilled staff with hours of dilution work instead of analysis, impacting both operational efficiency and job satisfaction. For over two decades, Endosafe® cartridge technology has helped quality control labs streamline bacterial endotoxin testing (BET) while meeting compendial standards. In 2014, the first fully automated robotic Endosafe Nexus brought walk-away automation to large-scale QC labs. The Nexus 200 builds on that foundation, doubling capacity, adding complex dilution capability, and integrating new data integrity tools. The Nexus 200 automates the full endotoxin testing workflow in one enclosed, integrated platform. Analysts load samples, consumables, and cartridges