Rapid syphilis test DPP®

HIVTreponema pallidumplasma

An FDA Approved, CLIA Waived* dual rapid test for the detection of antibodies to HIV 1/2 and Treponema pallidum in fingerstick whole blood, venous whole blood, or plasma specimens. Reliable Built-in procedural control Easy to Use Provides objective results using simple, handheld digital reader (DPP® Micro Reader) Economical Ideal as the first line rapid test in your algorithm Are there other confirmatory tests needed when using these rapids? In the reverse testing algorithm for syphilis, you will need to reflex to RPR to find out if you have an active or past infection. For HIV you would need to confirm a positive based on your site’s protocols. Could temperature be a factor when using this test in the field or on the street? The test components should be at room temperature, 18 to 25 C (64 to 77  F), before performing the test and the test should be performed within the same temperature range. If the temperature of the testing area falls outside of 18 to 25 C (64 to 77 F) it is recommended to perform QC prior to testing. Is this test 4th generation for HIV? We do not detect antigen to HIV, just antibodies to HIV, the following papers support this approach to the rapid HIV Testing. The paper ‘Field Accuracy of fourth Generation Rapid Test’ by Lewis et al analyzed 4 studies that included 17,381 samples screened using 4th generation (Antigen-Antibody) rapid tests. Findings: 26 reference-standard-defined acute HIV infections were missed 35 false positives were observed Lesson’s Learned: ‘Fourth-generation RDTs are currently unsuitable for the detection of acute HIV-1’ at the point of care.