Automated, parallel library synthesis / lead optimization in drug discovery / medicinal chemistry.
OVERVIEW
Chemspeed's solution
Medicinal chemistry is driven more and more by the demand for innovative, better medicines which involves molecular diversity and novel routes, meaning more and more experiments typically with the same amount of resources.
Chemspeed’s fully automated, integrated FLEX ISYNTH stands for a flexible, modular, and uncompromising automated solution that unlocks the chemical space via faster, better, virtually unrestricted “off-road” chemistry investigation of the reaction space, reagent space or molecule space.
It also enhances your efficiency and productivity by a factor of up to 100, for example in:
C-C, C-N coupling reactions
Organometallic reactions (e.g. Grignard)
Alkylations
Diels-Alder reactions
Transfer hydrogenations
WORKFLOW
Example workflow
The interactive workflow panel below showcases example workflows for this solution. Each Chemspeed tool or module performs a set of specific actions, as in any manual lab workflow, and an almost limitless arrangement of these tools is possible.
BENEFITS
Powerful advantages
Fully automated, integrated reaction preparation, synthesis, work-up, analysis, output to storage vials for solid- and liquid-phase library synthesis.
Easy-to-use disposable multi-functional, high-precision glass reactor arrays with available reaction scales from μL to mL, screwless and self-sealing opening / closing, mixing by shaking (up to 1'000 rpm without cover).