Automated sample preparation system FLEX SWILE NMR

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Step-change in end-to-end NMR and LCMS sample preparation - gravimetric pick & decision dispense of solids / matrix-to-matrix reformatting (incl. applications in GMP environments). OVERVIEW Chemspeed's solution Nuclear magnetic resonance (NMR) is a method of physical observation in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field and therefore not involving electromagnetic waves) and respond by producing an electromagnetic signal with a frequency characteristic of the magnetic field at the nucleus. NMR results from specific magnetic properties of certain atomic nuclei. Nuclear magnetic resonance spectroscopy is widely used to determine the structure of organic molecules in solution and study molecular physics, crystals as well as non-crystalline materials. NMR is also routinely used in advanced medical imaging techniques, such as in magnetic resonance imaging (MRI). However, the preparation of NMR samples is often still done manually and binds highly qualified resources to very time-consuming, tedious and error-prone tasks. The SWILE technology enables automated true one-to-one gravimetric "pick & decision dispense" of solid compounds. The scheme at the bottom of this page displays the simplified SWILE workflow including the precision "pick & decision dispense" step. The technology backbone is based on Chemspeed’s proprietary overhead gravimetric dispensing tool design in combination with a second analytical on-deck-balance. In order to exclude any risk of cross-contamination disposable glass tips are used which are stored and provided by the automated SWIN dispenser.