Automated small-molecule reaction screening (μL to mL scale) in e.g. late-stage drug discovery / lead optimization.
OVERVIEW
Chemspeed's solution
Our overhead gravimetric (patented) dispensing of solids & liquids combined with our fully automated small-scale reactor formats (μL to mL scale) and our user-friendly software boost you to accelerate, standardize and digitize your small-molecule reaction screening (incl. reaction preparation, photochemistry, work-up, analysis).
WORKFLOW
Example workflow
The interactive workflow panel below showcases example workflows for this solution. Each Chemspeed tool or module performs a set of specific actions, as in any manual lab workflow, and an almost limitless arrangement of these tools is possible.
BENEFITS
Powerful advantages
Decrease in cost per experiment up to 90+ %.
Increase in productivity by a factor of 10+.
Easy-to-use disposable glass reactors / vials and / or reusable double-jacket reactors.
Small-scale synthesis at ambient pressure & up to 100 bar.
Enabled by SWILE (one-to-one / many-to-many gravimetric pick & dispense of solids).
Mixing by shaking or tumble stirring.
Reagent preparation (liquids and solids), multistep synthesis, work-up, purification, analysis and product transfer to storage.
Ventilated, conditioned hood for e.g. sensitive, low-temperature chemistry - 70 to 200 °C.
4-Needle Head for volumetric liquid handling and sampling.
Gravimetric solid dispensing into an unlimited choice of vial / plate / reactor formats.
The balance moves to the destination, increasing speed and efficiency.