Parallel, automated and real-time calorimetry in high-precision Qbd process reactors for e.g. safety.
Overview
Chemspeed's solution
The leading technology in overhead gravimetric dispensing / dosing (patented) combined with our quality by design reactor technology as wella process excellence and user-friendly software enable you to accelerate, standardize and digitalize your calorimetry workflows.
Workflow
Example workflow
The interactive workflow panel below showcases example workflows for this solution. Each Chemspeed tool or module performs a set of specific actions, as in any manual lab workflow, and an almost limitless arrangement of these tools is possible.
Benefits
Powerful advantages
Each reactor with its own set of conditions - individually controlled tank reactors (reactor volumes 100, 240, 1’000 mL total volume) with precise, continuous feeds:
Up to 12 / 24 calorimetry experiments per run on an AUTOPLANT, up to 6 per run on a semi-automated MULTIPLANT.
Independent control of all process parameters in each reactor with in-situ calorimetry and e.g. NIR, pH.
Independent, precise temperature and stirring control in each reactor (e.g. 130°C temperature difference between adjacent reactors, with active cooling >>130°C).
Internal and / or jacket temperature control.
Multiple independent gas, liquefied gas and liquid feeds per reactor.
Gravimetric solid and viscous liquid dispensing.
4-Needle Head for volumetric liquid handling and sampling.
Feeding and sampling under reaction conditions.
Cleaning in place (e.g. automated cleaning, inserts).
Extraction, filtration, evaporation, crystallization, distillation.