This Fluorescent Immunoassay VEGF POCT Kit is designed for in vitro quantitative detection of VEGF amount in whole blood ,serum and plasma samples. It’s for professional only.
Summary
VEGF(Vascular endothelial growth factor),was originally known as VEGF A before it was first named in 1989 with a molecular weight of approximately 45 kDa. VEGF family is a signal protein produced by many cells that stimulates the formation of blood vessels, involving in both vasculogenesis and angiogenesis. To be specific,it is the key mediator of angiogenesis that is the development of new blood vessels from pre-existing vasculature, and has important roles in growth and development, wound healing and tumorigenesis. In blood,VEGF may be located in the plasma, or in the blood-borne cells and formed elements, in particular, platelets and leukocytes.
Why Test VEGF ?
VEGF's normal function is to create new blood vessels during embryonic development, new blood vessels after injury, muscle following exercise, and new vessels (collateral circulation) to bypass blocked vessels.
It can contribute to disease.
The body makes more VEGF in certain cases where it needs angiogenesis,overexpression of VEGF can cause vascular disease. Solid cancers cannot grow beyond a limited size without an ample blood supply. VEGF is the key mediator of angiogenesis in cancer, in which it is up-regulated by oncogene expression, a variety of growth factors and also hypoxia. Many tumors produce large quantities of VEGF.
This fluorescent immunoassay VEGF POCT kit find out how quickly a tumor is growing by continuous monitoring of vegf blood test.