Pregnancy test kit LYOFIA® PAMG-1

fibronectinvaginal secretionsimmunoassay

This Fluorescent Immunoassay fFN POCT Kit is designed for in vitro quantitative detection of fFN in vaginal secretions samples. It’s for professional only. Summary fFN, the abbreviation of fetal Fibronectin, is an extracellular matrix glycoprotein produced by decidua and villi, which mainly plays the role of adhesion between placenta and decidua, and fFN can be positive before 20 weeks of pregnancy and before delivery. During the 22-35 weeks of pregnancy, the fetal membrane and decidua are completely fused. Under normal circumstances, the fFN detection should be <50ng/mL. If the fetal membrane and decidua are separated, the fFN detection result can exceed 50ng/mL. Principle The fluorescent immunoassay fFN POCT kit adopts microfluidic fluorescence immunoluminescence method, which helps get more accurate fFN level results in 10 minutes. Why Test fFN? Fetal fibronectin (fFN) is a reliable test to identify if pregnant women between 22 weeks and 35weeks of pregnancy who are most at risk for preterm birth and are having symptoms of premature labor will delivery preterm within the next 7-14 days, which is for reducing the risk of preterm birth. If fFN is present in vaginal discharge, it is highly correlated with preterm birth.After 24 weeks, under normal circumstances, fibronectin should not be detected in the secretion of the vaginal posterior curvature (fibronectin <50) The positive fibronectin in the vaginal posterior curvature secretion in the first trimester is caused by the separation of chorion and decidua. Fibronectin leaks into vaginal fornix discharge. The detection by the fluorescent immunoassay fFN POCT kit can have negative and positive result.